Tramadol is a unique compound with both a moderate mu-opioid effect (when compared to classic opioids) and a moderate monoaminergic effect (when compared to tricyclic antidepressants). Tramadol has a more acceptable side-effect profile in comparison with tricyclic antidepressants and antiepileptics. Although possible, tolerance and dependence pose uncommon complications of the treatment. Out of the four main pain types, the action of Tramadol is not limited to neuropathic pain only but also includes suppression of noxious (nociceptive) pains.
Classification of Tramadol-Manageable Pain Types:
Neuropathic pain arises spontaneously or regularly from damaged nerves. The neural signals behind neuropathic pain are unlike those channeled from damaged tissue (which can appear as the result of a fall, a cut or a burn) along healthy nerves.